Dicer (DICER1 or DCR1) Antibody - Western Blot Validated
BiCell Scientific
SKU:51703-WB-50UL
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Protein Function
For consistent comparison across experiments, use this antibody to investigate Dicer with a repeatable workflow. Dicer is a signaling node often evaluated by abundance, localization, and modification-dependent states. Use matched handling so differences reflect biology rather than processing.
In some datasets and protocols, it is referenced by the gene symbol DCR1.
Experimental Applications
Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.
Common experimental questions that benefit from target tracking include:
- condition-to-condition comparisons with matched controls
- interaction patterns within multi-protein complexes
- time-resolved changes following stimulation or inhibition
- localization shifts between cytoplasm, membrane, and nucleus
Workflow Perspective
When samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Document normalization choices so collaborators can reproduce the same interpretation.
If your study spans multiple model systems, it can help to define a shared reference condition for Dicer so cross-sample contrasts stay meaningful.
For multi-run studies, the denaturing-format option helps keep Dicer trends comparable from experiment to experiment.
- Targets:
- DICER1
- Research Area:
- Cell Signaling • Epigenetics
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal region of human Dicer protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9UPY3
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C