Diltiazem

1 1

Selleck Chemicals

E7160-100MG

€144,00 EUR
€144,00 EUR
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Diltiazem is an antagonist of Calcium Channels used in studies of Calcium Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to calcium flux, excitability, and secretion-linked signaling in cardiovascular, cell signaling, and neuroscience models.

By blocking Calcium Channels, Diltiazem can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cardiovascular, cell signaling, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Calcium Channels
  • Pathway perturbation studies connected to Calcium Signaling
  • Receptor-blockade and ligand-competition studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, Diltiazem is appropriate when a defined chemical perturbant is needed to connect Calcium Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, cell signaling, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Calcium Channels
Target Class:
Ion Channel
Pathways:
Calcium Signaling
Research Area:
Cardiovascular • Cell Signaling • Neuroscience
CAS No.:
42399-41-7
Molecular Weight:
414.52
Formula:
C₂₂H₂₆N₂O₄S
SMILES:
COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O)cc1
InChIKey:
HSUGRBWQSSZJOP-RTWAWAEBSA-N
PubChem:
39186
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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