DNMT1 (DNMT) Antibody - FFPE Validated
BiCell Scientific
SKU:82021-FFPE-50UL
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Scientific Overview
Bring DNMT1 into view to investigate changes across conditions. DNMT1 is a target that supports characterization of cellular state through expression and localization readouts. Look for shifts in distribution that track with phenotype changes.
Tracking DNMT1 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Relevance
Temporal sampling and matched controls can improve interpretation when expression is dynamic. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- cross-sample normalization strategies
- baseline versus stimulated condition comparisons
- interpretation alongside orthogonal readouts
- subcellular compartment mapping
Application-Specific Context
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
For challenging targets, pairing DNMT1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so DNMT1 patterns can be compared across experiments without guesswork.
Choose the fixed-section option when you want DNMT1 results aligned to your sample format.
- Targets:
- DNMT1
- Research Area:
- Epigenetics
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the N-terminal region of mouse DNMT1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P26358
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 92.9% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C