DPI (Diphenyleneiodonium chloride)
Selleck Chemicals
SKU:S8639-10MG
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DPI (Diphenyleneiodonium chloride) is an inhibitor of ROS and TRP Channels used in studies of Calcium Signaling and Oxidative Stress Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to calcium flux, excitability, and secretion-linked signaling and redox signaling, ROS handling, and antioxidant defenses in cell signaling, immunology, and inflammation models.
By inhibiting ROS and TRP Channels, DPI (Diphenyleneiodonium chloride) can be used to examine calcium flux, excitability, and secretion-linked signaling and redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In cell signaling, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving ROS and TRP Channels
- Pathway perturbation studies connected to Calcium Signaling and Oxidative Stress Response
- Concentration-response inhibition and target-dependence studies
- Pathway-reporter and mechanistic-phenotyping studies
Overall, DPI (Diphenyleneiodonium chloride) is appropriate when a defined chemical perturbant is needed to connect ROS and TRP Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- ROS • TRP Channels
- Target Class:
- Signaling Pathway Modulator
- Pathways:
- Calcium Signaling • Oxidative Stress Response
- Research Area:
- Cell Signaling • Immunology • Inflammation • Neuroscience
- CAS No.:
- 4673-26-1
- Molecular Weight:
- 314.55
- Formula:
- C₁₂H₈I·Cl
- SMILES:
- C1=CC=C2C(=C1)C3=CC=CC=C3[I+]2.[Cl-]
- InChIKey:
- FCFZKAVCDNTYID-UHFFFAOYSA-M
- PubChem:
- 2733504
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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