DTHIB

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Selleck Chemicals

S9806-5MG

€144,00 EUR
€144,00 EUR
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DTHIB is an inhibitor of HSP90 used in studies of target-focused biology. It is especially relevant in cancer and protein homeostasis models, where defined compound exposure can be linked to annotated target biology and downstream cellular responses.

By inhibiting HSP90, DTHIB can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with concentration-response inhibition and target-dependence studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In cancer and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HSP90
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer and protein homeostasis models
  • Combination studies with orthogonal perturbagens

Overall, DTHIB is appropriate when a defined chemical perturbant is needed to connect HSP90 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HSP90
Target Class:
Other
Research Area:
Cancer • Protein Homeostasis
CAS No.:
897326-30-6
Molecular Weight:
309.68
Formula:
C₁₃H₉ClFN₃O₃
SMILES:
[O-][N+](=O)C1=CC(=CC=C1Cl)NC(=O)NC2=CC=C(F)C=C2
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.