Dystrophin (DMD) Antibody

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BiCell Scientific

SKU:54710-50UL

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Size
Blocking Peptide
Quantity
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About the Target

This antibody is suited for researchers who want to investigate Dystrophin and relate it to cell-state biology. Dystrophin is a filament-associated component linked to spatial organization within cells. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

Following Dystrophin across perturbations can help separate expression effects from compartment shifts.

Research Context

Because cytoskeletal proteins can be abundant, interpretation benefits from attention to dynamic range and saturation. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.

Consider these angles when interpreting target-level changes:

  • stress-fiber versus cortical distribution patterns
  • association with junctional complexes or focal adhesions
  • remodeling after perturbation of polymerization or contractility

Variant Considerations

When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

If your study spans multiple model systems, it can help to define a shared reference condition for Dystrophin so cross-sample contrasts stay meaningful.

When interpreting Dystrophin, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

The regular format version supports deeper biological narratives around Dystrophin without overcomplicating setup.

Targets:
DMD
Research Area:
Cardiovascular
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (15-aa) derived from the C-terminal region of mouse dystrophin protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P11532
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 93.3% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C