E-cadherin (Cdh1 or CD324) Antibody

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BiCell Scientific

SKU:00101-50UL

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Size
Blocking Peptide
Quantity
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About the Target

This antibody enables you to explore E-cadherin with a direct, biology-first readout. E-cadherin is a junctional protein that coordinates adhesion with cytoskeletal anchoring. Focus on trends across conditions rather than single-point snapshots.

In some datasets and protocols, it is referenced by the gene symbol CD324.

Research Context

Shifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Pair measurements with orthogonal readouts when interpretation is sensitive to context. Developmental projects may follow this target across stage-dependent remodeling and tissue patterning.

Consider these angles when interpreting target-level changes:

  • co-localization patterns with cytoskeletal elements
  • subcellular redistribution at contact sites versus cytoplasm
  • comparative profiling across cell states or perturbations
  • changes in complex assembly with scaffold or adaptor proteins

Variant Considerations

If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

If your study spans multiple model systems, it can help to define a shared reference condition for E-cadherin so cross-sample contrasts stay meaningful.

When interpreting E-cadherin, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

Select the regular format version to keep E-cadherin interpretation aligned with your workflow goals.

Targets:
CDH1
Research Area:
Developmental Biology
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (13-aa) derived from the C-terminal region of human E-cadherin protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P12830
Homology:
Synthetic peptide sequence is identical to mouse or rat sequence (this sequence has no homology to other cadherin isoforms)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C