Elacridar hydrochloride
Selleck Chemicals
SKU:E7515
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Elacridar hydrochloride is an inhibitor of P-gp used in studies of transporter biology. It is especially relevant in cancer, immunology, and inflammation models, where defined compound exposure can be linked to substrate uptake, efflux, and membrane-transport control.
By inhibiting P-gp, Elacridar hydrochloride can be used to examine substrate uptake, efflux, and membrane-transport control. This target class is commonly examined through transport, uptake/efflux, and permeability assays, together with downstream-response mapping. In cancer, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving P-gp
- Concentration-response inhibition and target-dependence studies
- Transport, uptake/efflux, and permeability assays
- Phenotypic profiling in cancer, immunology, and inflammation models
Overall, Elacridar hydrochloride is appropriate when a defined chemical perturbant is needed to connect P-gp with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- P-gp
- Target Class:
- Transporter
- Research Area:
- Cancer • Immunology • Inflammation • Infectious Disease
- CAS No.:
- 143851-98-3
- Molecular Weight:
- 600.10
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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