Elesclomol (STA-4783)

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Selleck Chemicals

S1052-5MG

€144,00 EUR
€144,00 EUR
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Elesclomol (STA-4783) is a modulator of HSP90 used in studies of Apoptosis. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and oxidative stress models.

By modulating HSP90, Elesclomol (STA-4783) can be used to examine caspase-associated cell-death signaling and survival decisions. This context is compatible with apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and oxidative stress models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HSP90
  • Pathway perturbation studies connected to Apoptosis
  • Context-dependent response profiling and mechanism comparison
  • Phenotypic profiling in apoptosis, cancer, and oxidative stress models

Overall, Elesclomol (STA-4783) is appropriate when a defined chemical perturbant is needed to connect HSP90 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and oxidative stress models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HSP90
Target Class:
Other
Pathways:
Apoptosis
Research Area:
Apoptosis • Cancer • Oxidative Stress • Protein Homeostasis
CAS No.:
488832-69-5
Molecular Weight:
400.5
Formula:
C₁₉H₂₀N₄O₂S₂
SMILES:
CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2
InChIKey:
BKJIXTWSNXCKJH-UHFFFAOYSA-N
PubChem:
300471
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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