Elimusertib (BAY-1895344)hydrochloride

1 1

Selleck Chemicals

S8666-2MG

€144,00 EUR
€144,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

Elimusertib (BAY-1895344)hydrochloride is an inhibitor of ATR and ATM used in studies of DNA Damage Response. It is especially relevant in cancer, cell signaling, and dna damage / repair models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control.

By inhibiting ATR and ATM, Elimusertib (BAY-1895344)hydrochloride can be used to examine checkpoint activation, DNA repair, and genome-stability control. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ATR and ATM
  • Pathway perturbation studies connected to DNA Damage Response
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Elimusertib (BAY-1895344)hydrochloride is appropriate when a defined chemical perturbant is needed to connect ATR and ATM with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ATR • ATM
Target Class:
Kinase
Pathways:
DNA Damage Response
Research Area:
Cancer • Cell Signaling • DNA Damage / Repair
Molecular Weight:
411.89
Formula:
C₂₀H₂₂ClN₇O
SMILES:
CC1COCCN1C2=NC3=C(C=CN=C3C4=CC=NN4)C(=C2)C5=CC=NN5C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.