ENaC beta (Scnn1b) (Human) Antibody - Western Blot Validated
BiCell Scientific
SKU:20342H-WB-50UL
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About the Target
Use this antibody to analyze ENaC beta (Scnn1b) when mapping complex behavior and signaling context. ENaC beta is a membrane-embedded regulator of ionic or osmotic balance in cells. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol Scnn1b.
Research Context
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Consider these angles when interpreting target-level changes:
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
Variant Considerations
If your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting ENaC beta, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
When interpreting ENaC beta, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the denaturing-format version to relate ENaC beta (Scnn1b) behavior to upstream cues and downstream consequences.
- Targets:
- SCNN1B
- Research Area:
- Metabolism • Neuroscience
- Application:
- WB
- Reactivity:
- Human
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal cytoplasmic region of human ENaC beta subunit protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P51168
- Homology:
- Synthetic peptide sequence showing 64.3% homology to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C