ENaC gamma (Scnn1g) Antibody
BiCell Scientific
SKU:20343-50UL
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About the Target
This antibody supports efforts to evaluate ENaC gamma (Scnn1g) and interpret it within interaction networks. ENaC gamma is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol Scnn1g.
Research Context
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution. Kidney-focused model systems may monitor this target when evaluating transport, barrier features, or compartment identity.
Consider these angles when interpreting target-level changes:
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
- patterns consistent with apical or basolateral sorting
Variant Considerations
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so ENaC gamma patterns can be compared across experiments without guesswork.
When interpreting ENaC gamma, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
The regular format option supports mechanistic reading of ENaC gamma (Scnn1g) when interactions and context are the focus.
- Targets:
- SCNN1G
- Research Area:
- Metabolism • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal cytoplasmic region of mouse ENaC gamma subunit protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P51170
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 66.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C