Ensartinib dihydrochloride

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Selleck Chemicals

S2934-2MG

€144,00 EUR
€144,00 EUR
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Ensartinib dihydrochloride is an inhibitor of ALK and ROS1 and related targets used in studies of MAPK / ERK Signaling. It is especially relevant in angiogenesis, cancer, and cell signaling models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling.

By inhibiting ALK and ROS1 and related targets, Ensartinib dihydrochloride can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ALK and ROS1 and related targets
  • Pathway perturbation studies connected to MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Ensartinib dihydrochloride is appropriate when a defined chemical perturbant is needed to connect ALK and ROS1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ALK • ROS1 • Trk Receptors
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling
Research Area:
Angiogenesis • Cancer • Cell Signaling • Neuroscience
CAS No.:
2137030-98-7
Molecular Weight:
634.36
Formula:
C₂₆H₂₉Cl₄FN₆O₃
SMILES:
CC1CN(CC(N1)C)C(=O)C2=CC=C(C=C2)NC(=O)C3=NN=C(C(=C3)OC(C)C4=C(C=CC(=C4Cl)F)Cl)N.Cl.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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