EPH receptor A1 (EPHA1) Antibody - Western Blot Validated
BiCell Scientific
SKU:06014-WB-50UL
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Scientific Overview
This antibody supports efforts to investigate EPH receptor A1 and interpret it within interaction networks. EPH receptor A1 is a signaling component often monitored in models of neuronal differentiation and plasticity. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Following EPH receptor A1 across perturbations can help separate expression effects from compartment shifts.
Research Relevance
Perturbations that alter activity or trafficking can shift localization between soma, neurites, and synaptic regions. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
When building a narrative around the target, it helps to track:
- activity-linked changes in abundance or distribution
- comparison across differentiation time courses
- regional localization along neurites and synaptic compartments
Application-Specific Context
When samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.
The denaturing-format option supports mechanistic reading of EPH receptor A1 when interactions and context are the focus.
- Targets:
- EPHA1
- Research Area:
- Cell Signaling • Developmental Biology • Neuroscience
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal intracellular region of human EPH receptor A1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P21709
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C