ETC-206 (AUM 001)

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Selleck Chemicals

S6658-5MG

€223,00 EUR
€223,00 EUR
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ETC-206 (AUM 001) is an inhibitor of MNK used in studies of MAPK / ERK Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer and cell signaling models.

By inhibiting MNK, ETC-206 (AUM 001) can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving MNK
  • Pathway perturbation studies connected to MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, ETC-206 (AUM 001) is appropriate when a defined chemical perturbant is needed to connect MNK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
MNK
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling
Research Area:
Cancer • Cell Signaling
CAS No.:
1464151-33-4
Molecular Weight:
408.45
Formula:
C₂₅H₂₀N₄O₂
SMILES:
C1COCCN1C(=O)C2=CC=C(C=C2)C3=CN4C(=NC=C4C5=CC=C(C=C5)C#N)C=C3
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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