Euphorbiasteroid

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Selleck Chemicals

SKU:S3832-5MG

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Euphorbiasteroid is an activator of AMPK used in studies of PI3K-Akt-mTOR Signaling and Apoptosis. It is especially relevant in apoptosis, autophagy, and cancer models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and caspase-associated cell-death signaling and survival decisions.

By activating AMPK, Euphorbiasteroid can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and caspase-associated cell-death signaling and survival decisions. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving AMPK
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Apoptosis
  • Gain-of-function pathway-activation studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Euphorbiasteroid is appropriate when a defined chemical perturbant is needed to connect AMPK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
AMPK
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • Apoptosis
Research Area:
Apoptosis • Autophagy • Cancer • Cell Signaling
CAS No.:
28649-59-4
Molecular Weight:
552.66
Formula:
C₃₂H₄₀O₈
SMILES:
CC1CC2(C(C1OC(=O)CC3=CC=CC=C3)C(C4(CCC5C(C5(C)C)C=C(C2=O)C)CO4)OC(=O)C)OC(=O)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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