FBXW11 (BTRCP2 or NEDJED) (C-Terminus) Antibody - FFPE Validated
BiCell Scientific
SKU:51611C-FFPE-50UL
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Scientific Overview
Use this antibody to evaluate FBXW11 C-Terminus in your model system. FBXW11 C-Terminus is a signaling node often evaluated by abundance, localization, and modification-dependent states. Focus on trends across conditions rather than single-point snapshots.
In some datasets and protocols, it is referenced by the gene symbol BTRCP2.
Research Relevance
When comparing conditions, consistent sample handling and normalization are key for meaningful contrasts. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- condition-to-condition comparisons with matched controls
- interaction patterns within multi-protein complexes
- localization shifts between cytoplasm, membrane, and nucleus
- time-resolved changes following stimulation or inhibition
Application-Specific Context
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
When interpreting FBXW11 C-Terminus, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
If your study spans multiple model systems, it can help to define a shared reference condition for FBXW11 C-Terminus so cross-sample contrasts stay meaningful.
With a clear focus on FBXW11 C-Terminus, this fixed-section option fits streamlined studies and fast iteration.
- Targets:
- FBXW11
- Research Area:
- Cell Signaling
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal region of human FBXW11 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9UKB1
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C