Fendiline hydrochloride

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Selleck Chemicals

SKU:S5279-25MG

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Fendiline hydrochloride is an inhibitor of Calcium Channels and KRAS used in studies of MAPK / ERK Signaling and Calcium Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and calcium flux, excitability, and secretion-linked signaling in cancer, cardiovascular, and cell signaling models.

By inhibiting Calcium Channels and KRAS, Fendiline hydrochloride can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cancer, cardiovascular, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Calcium Channels and KRAS
  • Pathway perturbation studies connected to MAPK / ERK Signaling and Calcium Signaling
  • Concentration-response inhibition and target-dependence studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, Fendiline hydrochloride is appropriate when a defined chemical perturbant is needed to connect Calcium Channels and KRAS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cardiovascular, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Calcium Channels • KRAS
Target Class:
Ion Channel
Pathways:
MAPK / ERK Signaling • Calcium Signaling
Research Area:
Cancer • Cardiovascular • Cell Signaling • Neuroscience
CAS No.:
13636-18-5
Molecular Weight:
351.91
Formula:
C₂₃H₂₅N·HCl
SMILES:
CC(C1=CC=CC=C1)NCCC(C2=CC=CC=C2)C3=CC=CC=C3.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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