FH535

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Selleck Chemicals

S7484-25MG

€193,00 EUR
€193,00 EUR
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FH535 is an inhibitor of Wnt / beta-catenin and PPAR delta and related targets used in studies of Wnt Signaling and Metabolic Signaling. In practice, this places the compound in experiments that measure beta-catenin-dependent transcription and developmental signaling and metabolic regulation, energy sensing, and enzyme-linked homeostasis in cancer, cell signaling, and developmental biology models.

By inhibiting Wnt / beta-catenin and PPAR delta and related targets, FH535 can be used to examine beta-catenin-dependent transcription and developmental signaling and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Wnt / beta-catenin and PPAR delta and related targets
  • Pathway perturbation studies connected to Wnt Signaling and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, FH535 is appropriate when a defined chemical perturbant is needed to connect Wnt / beta-catenin and PPAR delta and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Wnt / beta-catenin • PPAR delta • PPAR gamma
Target Class:
Nuclear Receptor
Pathways:
Wnt Signaling • Metabolic Signaling
Research Area:
Cancer • Cell Signaling • Developmental Biology • Endocrinology
CAS No.:
108409-83-2
Molecular Weight:
361.20
Formula:
C₁₃H₁₀Cl₂N₂O₄S
SMILES:
CC1=C(C=CC(=C1)[N+](=O)[O-])NS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.