Filamin A (FLNA) Antibody
BiCell Scientific
SKU:30091-50UL
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Scientific Overview
This antibody enables you to evaluate Filamin A with a direct, biology-first readout. Filamin A is a filament-associated component linked to spatial organization within cells. Look for shifts in distribution that track with phenotype changes.
In some datasets and protocols, it is referenced by the gene symbol FLNA.
Research Relevance
Cytoskeletal targets are often examined during migration, adhesion changes, and responses to mechanical cues. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.
When building a narrative around the target, it helps to track:
- differences across cell density or substrate stiffness
- remodeling after perturbation of polymerization or contractility
- stress-fiber versus cortical distribution patterns
- association with junctional complexes or focal adhesions
Application-Specific Context
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
For challenging targets, pairing Filamin A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
If your study spans multiple model systems, it can help to define a shared reference condition for Filamin A so cross-sample contrasts stay meaningful.
Choose the regular format option when you want Filamin A results aligned to your sample format.
- Targets:
- FLNA
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of human Filamin A protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P21333
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C