Filamin A (FLNA) Antibody

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BiCell Scientific

SKU:30091-50UL

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Blocking Peptide
Quantity
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Scientific Overview

This antibody enables you to evaluate Filamin A with a direct, biology-first readout. Filamin A is a filament-associated component linked to spatial organization within cells. Look for shifts in distribution that track with phenotype changes.

In some datasets and protocols, it is referenced by the gene symbol FLNA.

Research Relevance

Cytoskeletal targets are often examined during migration, adhesion changes, and responses to mechanical cues. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.

When building a narrative around the target, it helps to track:

  • differences across cell density or substrate stiffness
  • remodeling after perturbation of polymerization or contractility
  • stress-fiber versus cortical distribution patterns
  • association with junctional complexes or focal adhesions

Application-Specific Context

For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

For challenging targets, pairing Filamin A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

If your study spans multiple model systems, it can help to define a shared reference condition for Filamin A so cross-sample contrasts stay meaningful.

Choose the regular format option when you want Filamin A results aligned to your sample format.

Targets:
FLNA
Research Area:
Developmental Biology
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (18-aa) derived from the C-terminal region of human Filamin A protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P21333
Homology:
Synthetic peptide sequence is identical to mouse or rat sequence
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C