Filamin A (FLNA) Antibody - Western Blot Validated
BiCell Scientific
SKU:30091-WB-50UL
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About the Target
When you need to examine Filamin A (FLNA) with attention to cellular organization, this antibody provides a focused option. Filamin A is a structural protein that interfaces with actin, microtubules, or associated adaptors. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol FLNA.
Research Context
Comparative analysis across confluence states can reveal junctional coupling or stress-fiber reorganization. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- remodeling after perturbation of polymerization or contractility
- association with junctional complexes or focal adhesions
- stress-fiber versus cortical distribution patterns
Variant Considerations
This denaturing-format version is geared toward targets presented after reduction and denaturation, where epitope exposure can shift from native conformations. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing Filamin A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For challenging targets, pairing Filamin A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
As you refine hypotheses around Filamin A (FLNA), the denaturing-format format helps keep conclusions tied to preparation context.
- Targets:
- FLNA
- Research Area:
- Developmental Biology
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of human Filamin A protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P21333
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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