Filamin B (FLNB) Antibody
BiCell Scientific
SKU:30092-50UL
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About the Target
Designed to help you examine Filamin B (FLNB), this antibody supports studies where protein context matters. Filamin B is a scaffold that can coordinate signaling with cytoskeletal remodeling. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Following Filamin B across perturbations can help separate expression effects from compartment shifts.
Research Context
Cytoskeletal targets are often examined during migration, adhesion changes, and responses to mechanical cues. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- differences across cell density or substrate stiffness
- remodeling after perturbation of polymerization or contractility
- association with junctional complexes or focal adhesions
Variant Considerations
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing Filamin B measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
If your study spans multiple model systems, it can help to define a shared reference condition for Filamin B so cross-sample contrasts stay meaningful.
Use the regular format variant when your project demands Filamin B (FLNB) readouts that respect preparation constraints.
- Targets:
- FLNB
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the N-terminal region of human Filamin B protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- O75369
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C