Finerenone (BAY 94-8862)

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Selleck Chemicals

S9702-5MG

€146,00 EUR
€146,00 EUR
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Finerenone (BAY 94-8862) is an antagonist of Mineralocorticoid Receptor used in studies of Hormone Signaling. It is especially relevant in cardiovascular and endocrinology models, where defined compound exposure can be linked to ligand-dependent transcriptional programs and endocrine regulation.

By blocking Mineralocorticoid Receptor, Finerenone (BAY 94-8862) can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cardiovascular and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Mineralocorticoid Receptor
  • Pathway perturbation studies connected to Hormone Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Finerenone (BAY 94-8862) is appropriate when a defined chemical perturbant is needed to connect Mineralocorticoid Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Mineralocorticoid Receptor
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Cardiovascular • Endocrinology
CAS No.:
1050477-31-0
Molecular Weight:
378.42
Formula:
C₂₁H₂₂N₄O₃
SMILES:
CCOC1=NC=C(C)C2=C1C(C3=CC=C(C=C3OC)C#N)C(=C(C)N2)C(N)=O
InChIKey:
BTBHLEZXCOBLCY-UHFFFAOYSA-N
PubChem:
60150535
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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