Flavopiridol (Alvocidib)HCl

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Selleck Chemicals

S2679-10MG

€144,00 EUR
€144,00 EUR
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Flavopiridol (Alvocidib)HCl is an inhibitor of CDK and CDK1 and related targets used in studies of MAPK / ERK Signaling and Cell Cycle Regulation and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint control, mitotic progression, and proliferation timing in autophagy, cancer, and cell cycle models.

By inhibiting CDK and CDK1 and related targets, Flavopiridol (Alvocidib)HCl can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint control, mitotic progression, and proliferation timing. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving CDK and CDK1 and related targets
  • Pathway perturbation studies connected to MAPK / ERK Signaling and Cell Cycle Regulation and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Flavopiridol (Alvocidib)HCl is appropriate when a defined chemical perturbant is needed to connect CDK and CDK1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
CDK • CDK1 • CDK2 • CDK4
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling • Cell Cycle Regulation • Autophagy
Research Area:
Autophagy • Cancer • Cell Cycle • Cell Signaling
CAS No.:
131740-09-5
Molecular Weight:
438.3
Formula:
C₂₁H₂₀ClNO₅·HCl
SMILES:
CN1CCC(C(C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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