Frizzled-5 (FZD5) Antibody
BiCell Scientific
SKU:50605-50UL
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About the Target
This antibody is suited for researchers who want to evaluate Frizzled-5 and relate it to cell-state biology. Frizzled-5 is a signaling protein that can relay information through phosphorylation and complex assembly. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol FZD5.
Research Context
Signaling targets are typically assessed across time courses to capture transient activation windows. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions. Planar polarity studies may connect this target to directional signaling and cytoskeletal alignment.
Consider these angles when interpreting target-level changes:
- condition-to-condition comparisons with matched controls
- time-resolved changes following stimulation or inhibition
- interaction patterns within multi-protein complexes
Variant Considerations
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting Frizzled-5, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
If your study spans multiple model systems, it can help to define a shared reference condition for Frizzled-5 so cross-sample contrasts stay meaningful.
Use the regular format variant when your project demands Frizzled-5 readouts that respect preparation constraints.
- Targets:
- FZD5
- Research Area:
- Cell Signaling • Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal intracellular region of mouse frizzled-5 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q13467
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 86.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C