Frizzled-6 (FZD6) Antibody
BiCell Scientific
SKU:50606-50UL
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Protein Function
For consistent comparison across experiments, use this antibody to explore Frizzled-6 (FZD6) with a repeatable workflow. Frizzled-6 is a pathway component whose activation state and localization can change after stimulation. Use matched handling so differences reflect biology rather than processing.
In some datasets and protocols, it is referenced by the gene symbol FZD6.
Experimental Applications
Signaling targets are typically assessed across time courses to capture transient activation windows. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies. Planar polarity studies may connect this target to directional signaling and cytoskeletal alignment.
Common experimental questions that benefit from target tracking include:
- time-resolved changes following stimulation or inhibition
- interaction patterns within multi-protein complexes
- localization shifts between cytoplasm, membrane, and nucleus
- condition-to-condition comparisons with matched controls
Workflow Perspective
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Document normalization choices so collaborators can reproduce the same interpretation.
When interpreting Frizzled-6, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Pair this regular format format with stable controls to keep Frizzled-6 (FZD6) measurements coherent over time.
- Targets:
- FZD6
- Research Area:
- Cell Signaling • Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal intracellular region of mouse frizzled-6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- O60353
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 71.4% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C