GABRA1 Antibody

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BiCell Scientific

SKU:15101-50UL

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Size
Blocking Peptide
Quantity
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Scientific Overview

To connect mechanism with measurement, this antibody lets you examine GABRA1 in pathway-driven studies. GABRA1 is a channel or transporter associated with regulated flux across cellular membranes. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.

Tracking GABRA1 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.

Research Relevance

Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.

Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes. Neural differentiation and synaptic organization projects may include this target as a contextual readout.

When building a narrative around the target, it helps to track:

  • patterns consistent with apical or basolateral sorting
  • relative abundance across engineered constructs
  • surface versus intracellular pool distribution

Application-Specific Context

This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.

When interpreting GABRA1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

Choose the regular format format to study GABRA1 in a way that stays anchored to pathway logic.

Targets:
GABRA1
Research Area:
Cell Signaling • Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (13-aa) derived from the N-terminal extracellular region of mouse GABRA1 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P14867
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 92.9% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C