GABRA1 Antibody - FFPE Validated
BiCell Scientific
SKU:15101-FFPE-50UL
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Protein Function
This antibody enables you to characterize GABRA1 with a direct, biology-first readout. GABRA1 is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Focus on trends across conditions rather than single-point snapshots.
Following GABRA1 across perturbations can help separate expression effects from compartment shifts.
Experimental Applications
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Common experimental questions that benefit from target tracking include:
- patterns consistent with apical or basolateral sorting
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
- stimulus-dependent trafficking and turnover
Workflow Perspective
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
For challenging targets, pairing GABRA1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
If your study spans multiple model systems, it can help to define a shared reference condition for GABRA1 so cross-sample contrasts stay meaningful.
With a clear focus on GABRA1, this fixed-section option fits streamlined studies and fast iteration.
- Targets:
- GABRA1
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the N-terminal extracellular region of mouse GABRA1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P14867
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 92.9% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C