GABRA4 Antibody
BiCell Scientific
SKU:15104-50UL
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Biological Background
This antibody is suited for researchers who want to evaluate GABRA4 and relate it to cell-state biology. GABRA4 is a membrane-embedded regulator of ionic or osmotic balance in cells. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Monitoring GABRA4 alongside context markers can improve interpretation when phenotypes are subtle.
Use in the Laboratory
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Interpreting changes can benefit from separating expression differences from redistribution, particularly when the target cycles between compartments.
To keep datasets interpretable, labs often document:
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
- surface versus intracellular pool distribution
Version Notes
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.
If your study spans multiple model systems, it can help to define a shared reference condition for GABRA4 so cross-sample contrasts stay meaningful.
The regular format version supports deeper biological narratives around GABRA4 without overcomplicating setup.
- Targets:
- GABRA4
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the N-terminal extracellular region of mouse GABRA4 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P48169
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 84.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C