GABRA4 Antibody - FFPE Validated
BiCell Scientific
SKU:15104-FFPE-50UL
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About the Target
To connect mechanism with measurement, this antibody lets you characterize GABRA4 in pathway-driven studies. GABRA4 is a membrane protein linked to solute movement and gradient maintenance. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Monitoring GABRA4 alongside context markers can improve interpretation when phenotypes are subtle.
Research Context
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Consider these angles when interpreting target-level changes:
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
Variant Considerations
Because fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so GABRA4 patterns can be compared across experiments without guesswork.
When interpreting GABRA4, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
The fixed-section option supports mechanistic reading of GABRA4 when interactions and context are the focus.
- Targets:
- GABRA4
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the N-terminal extracellular region of mouse GABRA4 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P48169
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 84.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C