GABRA6 Antibody - FFPE Validated
BiCell Scientific
SKU:15106-FFPE-50UL
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Biological Background
This antibody enables you to evaluate GABRA6 with a direct, biology-first readout. GABRA6 is a channel or transporter associated with regulated flux across cellular membranes. Focus on trends across conditions rather than single-point snapshots.
Following GABRA6 across perturbations can help separate expression effects from compartment shifts.
Use in the Laboratory
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Depending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.
To keep datasets interpretable, labs often document:
- relative abundance across engineered constructs
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
- surface versus intracellular pool distribution
Version Notes
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.
When interpreting GABRA6, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
If your study spans multiple model systems, it can help to define a shared reference condition for GABRA6 so cross-sample contrasts stay meaningful.
With a clear focus on GABRA6, this fixed-section option fits streamlined studies and fast iteration.
- Targets:
- GABRA6
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the N-terminal extracellular region of mouse GABRA6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q16445
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 84.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C