Geldanamycin (NSC 122750)

1 1

Selleck Chemicals

S2713-5MG

€167,00 EUR
€167,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

Geldanamycin (NSC 122750) is an inhibitor of HSP90 used in studies of Hormone Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ligand-dependent transcriptional programs and endocrine regulation in cancer, endocrinology, and infectious disease models.

By inhibiting HSP90, Geldanamycin (NSC 122750) can be used to examine ligand-dependent transcriptional programs and endocrine regulation. This context is compatible with hormone-response, reporter, and receptor assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer, endocrinology, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HSP90
  • Pathway perturbation studies connected to Hormone Signaling
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer, endocrinology, and infectious disease models

Overall, Geldanamycin (NSC 122750) is appropriate when a defined chemical perturbant is needed to connect HSP90 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, endocrinology, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HSP90
Target Class:
Other
Pathways:
Hormone Signaling
Research Area:
Cancer • Endocrinology • Infectious Disease • Protein Homeostasis
CAS No.:
30562-34-6
Molecular Weight:
560.64
Formula:
C₂₉H₄₀N₂O₉
SMILES:
CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC
InChIKey:
QTQAWLPCGQOSGP-GBTDJJJQSA-N
PubChem:
5288382
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.