Ginkgolic acid C17:1
Selleck Chemicals
SKU:S0918-1MG
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Ginkgolic acid C17:1 is an inhibitor of STAT and JAK2 used in studies of MAPK / ERK Signaling and JAK-STAT Signaling and related signaling programs. It is especially relevant in apoptosis, cancer, and cell signaling models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-responsive transcriptional signaling and immune regulation.
By inhibiting STAT and JAK2, Ginkgolic acid C17:1 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-responsive transcriptional signaling and immune regulation. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving STAT and JAK2
- Pathway perturbation studies connected to MAPK / ERK Signaling and JAK-STAT Signaling and related signaling programs
- Concentration-response inhibition and target-dependence studies
- Pathway-reporter and mechanistic-phenotyping studies
Overall, Ginkgolic acid C17:1 is appropriate when a defined chemical perturbant is needed to connect STAT and JAK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- STAT • JAK2
- Target Class:
- Signaling Pathway Modulator
- Pathways:
- MAPK / ERK Signaling • JAK-STAT Signaling • Apoptosis
- Research Area:
- Apoptosis • Cancer • Cell Signaling • Immunology
- CAS No.:
- 111047-30-4
- Molecular Weight:
- 374.56
- Formula:
- C₂₄H₃₈O₃
- SMILES:
- CCCCCCC=CCCCCCCCCCC1=C(C(=CC=C1)O)C(=O)O
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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