Ginsenoside Rb3

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Selleck Chemicals

SKU:S9208-1MG

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Ginsenoside Rb3 is an inhibitor of NF-kB and COX and related targets used in studies of NF-kB Signaling and Immune Signaling. In practice, this places the compound in experiments that measure inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in cardiovascular, immunology, and inflammation models.

By inhibiting NF-kB and COX and related targets, Ginsenoside Rb3 can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cardiovascular, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NF-kB and COX and related targets
  • Pathway perturbation studies connected to NF-kB Signaling and Immune Signaling
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Ginsenoside Rb3 is appropriate when a defined chemical perturbant is needed to connect NF-kB and COX and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NF-kB • COX • COX-2
Target Class:
Enzyme
Pathways:
NF-kB Signaling • Immune Signaling
Research Area:
Cardiovascular • Immunology • Inflammation
CAS No.:
68406-26-8
Molecular Weight:
1079.27
Formula:
C₅₃H₉₀O₂₂
SMILES:
CC(C)=CCCC(C)(OC1OC(COC2OCC(O)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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