Glipizide

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Selleck Chemicals

SKU:S1715-50MG

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Glipizide is an inhibitor of Potassium Channels used in studies of ion-channel pharmacology. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ion conductance, membrane potential, and electrophysiological responses in cardiovascular and neuroscience models.

By inhibiting Potassium Channels, Glipizide can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cardiovascular and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Potassium Channels
  • Concentration-response inhibition and target-dependence studies
  • Electrophysiology, ion-flux, and membrane-potential studies
  • Phenotypic profiling in cardiovascular and neuroscience models

Overall, Glipizide is appropriate when a defined chemical perturbant is needed to connect Potassium Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Potassium Channels
Target Class:
Ion Channel
Research Area:
Cardiovascular • Neuroscience
CAS No.:
29094-61-9
Molecular Weight:
445.54
Formula:
C₂₁H₂₇N₅O₄S
SMILES:
CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
InChIKey:
ZJJXGWJIGJFDTL-UHFFFAOYSA-N
PubChem:
3478
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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