Glycyrrhizin (Glycyrrhizic Acid, NSC 167409)

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Selleck Chemicals

SKU:S2302-10MG

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Glycyrrhizin (Glycyrrhizic Acid, NSC 167409) is an inhibitor of Dehydrogenases and MAO used in studies of MAPK / ERK Signaling and Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and metabolic regulation, energy sensing, and enzyme-linked homeostasis in metabolism, neuroscience, and oxidative stress models.

By inhibiting Dehydrogenases and MAO, Glycyrrhizin (Glycyrrhizic Acid, NSC 167409) can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In metabolism, neuroscience, and oxidative stress models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Dehydrogenases and MAO
  • Pathway perturbation studies connected to MAPK / ERK Signaling and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Glycyrrhizin (Glycyrrhizic Acid, NSC 167409) is appropriate when a defined chemical perturbant is needed to connect Dehydrogenases and MAO with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in metabolism, neuroscience, and oxidative stress models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Dehydrogenases • MAO
Target Class:
Enzyme
Pathways:
MAPK / ERK Signaling • Metabolic Signaling
Research Area:
Metabolism • Neuroscience • Oxidative Stress
CAS No.:
1405-86-3
Molecular Weight:
822.93
Formula:
C₄₂H₆₂O₁₆
SMILES:
CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7)(C)C(=O)O)C)C)C)C
InChIKey:
LPLVUJXQOOQHMX-UHFFFAOYSA-N
PubChem:
7847225
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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