GRIA1 (GluR1 or GluA1) Antibody
BiCell Scientific
SKU:15131-50UL
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Scientific Overview
Use this antibody to assess GRIA1 in your model system. GRIA1 is a membrane protein linked to solute movement and gradient maintenance. Look for shifts in distribution that track with phenotype changes.
Following GRIA1 across perturbations can help separate expression effects from compartment shifts.
Research Relevance
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
When building a narrative around the target, it helps to track:
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
Application-Specific Context
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
For challenging targets, pairing GRIA1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
With a clear focus on GRIA1, this regular format option fits streamlined studies and fast iteration.
- Targets:
- GRIA1
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal cytoplasmic region of human GRIA1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P42261
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C