GSK-3 Inhibitor IX (BIO)

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Selleck Chemicals

S7198-10MG

€144,00 EUR
€144,00 EUR
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GSK-3 Inhibitor IX (BIO) is an inhibitor of GSK-3 used in studies of PI3K-Akt-mTOR Signaling and JAK-STAT Signaling and related signaling programs. It is especially relevant in apoptosis, cancer, and cell signaling models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and cytokine-responsive transcriptional signaling and immune regulation.

By inhibiting GSK-3, GSK-3 Inhibitor IX (BIO) can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and cytokine-responsive transcriptional signaling and immune regulation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving GSK-3
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and JAK-STAT Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, GSK-3 Inhibitor IX (BIO) is appropriate when a defined chemical perturbant is needed to connect GSK-3 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
GSK-3
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • JAK-STAT Signaling • Wnt Signaling
Research Area:
Apoptosis • Cancer • Cell Signaling • Developmental Biology
CAS No.:
667463-62-9
Molecular Weight:
356.17
Formula:
C₁₆H₁₀BrN₃O₂
SMILES:
C1=CC=C2C(=C1)C(=C(N2)C3=C(NC4=C3C=CC(=C4)Br)O)N=O
InChIKey:
DDLZLOKCJHBUHD-WAVHTBQISA-N
PubChem:
5287844
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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