GSK-923295
Selleck Chemicals
SKU:S7090-5MG
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GSK-923295 is an inhibitor of Kinesins used in studies of Cell Cycle Regulation and Apoptosis. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint control, mitotic progression, and proliferation timing and caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and cell cycle models.
By inhibiting Kinesins, GSK-923295 can be used to examine checkpoint control, mitotic progression, and proliferation timing and caspase-associated cell-death signaling and survival decisions. This context is compatible with cell-cycle, mitotic, and proliferation assays and apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Kinesins
- Pathway perturbation studies connected to Cell Cycle Regulation and Apoptosis
- Concentration-response inhibition and target-dependence studies
- Phenotypic profiling in apoptosis, cancer, and cell cycle models
Overall, GSK-923295 is appropriate when a defined chemical perturbant is needed to connect Kinesins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Kinesins
- Target Class:
- Other
- Pathways:
- Cell Cycle Regulation • Apoptosis
- Research Area:
- Apoptosis • Cancer • Cell Cycle
- CAS No.:
- 1088965-37-0
- Molecular Weight:
- 592.13
- Formula:
- C₃₂H₃₈ClN₅O₄
- SMILES:
- CC(C)OC1=C(C=C(C=C1)C(=O)NC(CC2=CC=C(C=C2)C3=CN4C=CC=C(C4=N3)C(C)O)CNC(=O)CN(C)C)Cl
- InChIKey:
- WHMXDBPHBVLYRC-UHFFFAOYSA-N
- PubChem:
- 46898058
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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