GSK0660

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Selleck Chemicals

S5817-5MG

€144,00 EUR
€144,00 EUR
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GSK0660 is an antagonist of PPAR used in studies of Hormone Signaling and Metabolic Signaling. It is especially relevant in endocrinology and metabolism models, where defined compound exposure can be linked to ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis.

By blocking PPAR, GSK0660 can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PPAR
  • Pathway perturbation studies connected to Hormone Signaling and Metabolic Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, GSK0660 is appropriate when a defined chemical perturbant is needed to connect PPAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PPAR
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
1014691-61-2
Molecular Weight:
418.49
Formula:
C₁₉H₁₈N₂O₅S₂
SMILES:
COC1=C(C=CC(=C1)NC2=CC=CC=C2)NS(=O)(=O)C3=C(SC=C3)C(=O)OC
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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