GSK2795039

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Selleck Chemicals

SKU:S8974-5MG

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GSK2795039 is an inhibitor of ROS used in studies of Apoptosis and Oxidative Stress Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions and redox signaling, ROS handling, and antioxidant defenses in apoptosis, cancer, and immunology models.

By inhibiting ROS, GSK2795039 can be used to examine caspase-associated cell-death signaling and survival decisions and redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ROS
  • Pathway perturbation studies connected to Apoptosis and Oxidative Stress Response
  • Concentration-response inhibition and target-dependence studies
  • Pathway-reporter and mechanistic-phenotyping studies

Overall, GSK2795039 is appropriate when a defined chemical perturbant is needed to connect ROS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ROS
Target Class:
Signaling Pathway Modulator
Pathways:
Apoptosis • Oxidative Stress Response
Research Area:
Apoptosis • Cancer • Immunology • Inflammation
CAS No.:
1415925-18-6
Molecular Weight:
450.56
Formula:
C₂₃H₂₆N₆O₂S
SMILES:
CC(C)N1C=C(C2=C(C=CN=C21)NS(=O)(=O)C3=NN(C=C3)C)C4=CC5=C(CCN5C)C=C4
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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