GSK3787

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Selleck Chemicals

S8025-10MG

€144,00 EUR
€144,00 EUR
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GSK3787 is an antagonist of PPAR and PPAR delta used in studies of Hormone Signaling and Metabolic Signaling. It is especially relevant in endocrinology and metabolism models, where defined compound exposure can be linked to ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis.

By blocking PPAR and PPAR delta, GSK3787 can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PPAR and PPAR delta
  • Pathway perturbation studies connected to Hormone Signaling and Metabolic Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, GSK3787 is appropriate when a defined chemical perturbant is needed to connect PPAR and PPAR delta with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PPAR • PPAR delta
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
188591-46-0
Molecular Weight:
392.78
Formula:
C₁₅H₁₂ClF₃N₂O₃S
SMILES:
C1=CC(=CC=C1C(=O)NCCS(=O)(=O)C2=NC=C(C=C2)C(F)(F)F)Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.