GSK5182

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Selleck Chemicals

S3449-5MG

€342,00 EUR
€342,00 EUR
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GSK5182 is an agonist of ERRgamma used in studies of Hormone Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation in endocrinology models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By activating ERRgamma, GSK5182 can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ERRgamma
  • Pathway perturbation studies connected to Hormone Signaling
  • Agonist-response and downstream signaling studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, GSK5182 is appropriate when a defined chemical perturbant is needed to connect ERRgamma with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ERRgamma
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Endocrinology
CAS No.:
877387-37-6
Molecular Weight:
417.54
Formula:
C₂₇H₃₁NO₃
SMILES:
CN(C)CCOC1=CC=C(C=C1)/C(=C(/CCCO)C2=CC=CC=C2)C3=CC=C(O)C=C3
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.