GW6471

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Selleck Chemicals

S2798-10MG

€144,00 EUR
€144,00 EUR
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GW6471 is an antagonist of PPAR alpha and PPAR used in studies of Hormone Signaling and Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.

By blocking PPAR alpha and PPAR, GW6471 can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PPAR alpha and PPAR
  • Pathway perturbation studies connected to Hormone Signaling and Metabolic Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, GW6471 is appropriate when a defined chemical perturbant is needed to connect PPAR alpha and PPAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PPAR alpha • PPAR
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
880635-03-0
Molecular Weight:
619.67
Formula:
C₃₅H₃₆F₃N₃O₄
SMILES:
CCC(=O)NCC(CC1=CC=C(C=C1)OCCC2=C(OC(=N2)C3=CC=CC=C3)C)NC(=CC(=O)C4=CC=C(C=C4)C(F)(F)F)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.