H2DCFDA (DCFH-DA)
Selleck Chemicals
SKU:S9687-25MG
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H2DCFDA (DCFH-DA) is a modulator of ROS used in studies of Oxidative Stress Response. In practice, this places the compound in experiments that measure redox signaling, ROS handling, and antioxidant defenses in immunology, inflammation, and metabolism models.
By modulating ROS, H2DCFDA (DCFH-DA) can be used to examine redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In immunology, inflammation, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving ROS
- Pathway perturbation studies connected to Oxidative Stress Response
- Context-dependent response profiling and mechanism comparison
- Pathway-reporter and mechanistic-phenotyping studies
Overall, H2DCFDA (DCFH-DA) is appropriate when a defined chemical perturbant is needed to connect ROS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology, inflammation, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- ROS
- Target Class:
- Signaling Pathway Modulator
- Pathways:
- Oxidative Stress Response
- Research Area:
- Immunology • Inflammation • Metabolism • Oxidative Stress
- CAS No.:
- 4091-99-0
- Molecular Weight:
- 487.29
- Formula:
- C₂₄H₁₆Cl₂O₇
- SMILES:
- CC(=O)OC1=CC2=C(C=C1Cl)C(C3=C(O2)C=C(OC(C)=O)C(=C3)Cl)C4=C(C=CC=C4)C(O)=O
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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