HA15

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Selleck Chemicals

SKU:S8299-5MG

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HA15 is a modulator of HSP90 used in studies of target-focused biology. In practice, this places the compound in experiments that measure annotated target biology and downstream cellular responses in cancer and protein homeostasis models.

By modulating HSP90, HA15 can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with context-dependent response profiling and mechanism comparison and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In cancer and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HSP90
  • Context-dependent response profiling and mechanism comparison
  • Phenotypic profiling in cancer and protein homeostasis models
  • Combination studies with orthogonal perturbagens

Overall, HA15 is appropriate when a defined chemical perturbant is needed to connect HSP90 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HSP90
Target Class:
Other
Research Area:
Cancer • Protein Homeostasis
CAS No.:
1609402-14-3
Molecular Weight:
466.58
Formula:
C₂₃H₂₂N₄O₃S₂
SMILES:
CC(=O)NC1=NC(=CS1)C2=CC(=CC=C2)NS(=O)(=O)C3=CC=CC4=C3C=CC=C4N(C)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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