Hispidulin

1 1

Selleck Chemicals

S3296-1MG

€95,00 EUR
€95,00 EUR
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Hispidulin is an inhibitor of PIM used in studies of PI3K-Akt-mTOR Signaling and JAK-STAT Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and cytokine-responsive transcriptional signaling and immune regulation in apoptosis, cancer, and cell signaling models.

By inhibiting PIM, Hispidulin can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and cytokine-responsive transcriptional signaling and immune regulation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PIM
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and JAK-STAT Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Hispidulin is appropriate when a defined chemical perturbant is needed to connect PIM with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PIM
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • JAK-STAT Signaling • Cell Cycle Regulation
Research Area:
Apoptosis • Cancer • Cell Signaling • Metabolism
CAS No.:
1447-88-7
Molecular Weight:
300.26
Formula:
C₁₆H₁₂O₆
SMILES:
COC1=C(O)C=C2OC(=CC(=O)C2=C1O)C3=CC=C(O)C=C3
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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