Homoplantaginin

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Selleck Chemicals

SKU:S9417-1MG

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Homoplantaginin is a natural-product modulator of IKK and NF-kB and related targets used in studies of JAK-STAT Signaling and NF-kB Signaling and related signaling programs. It is especially relevant in immunology and inflammation models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling.

By modulating IKK and NF-kB and related targets, Homoplantaginin can be used to examine cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving IKK and NF-kB and related targets
  • Pathway perturbation studies connected to JAK-STAT Signaling and NF-kB Signaling and related signaling programs
  • Context-dependent response profiling and mechanism comparison
  • Pathway-reporter and mechanistic-phenotyping studies

Overall, Homoplantaginin is appropriate when a defined chemical perturbant is needed to connect IKK and NF-kB and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
IKK • NF-kB • TNF-alpha • Interleukins
Target Class:
Signaling Pathway Modulator
Pathways:
JAK-STAT Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Immunology • Inflammation
CAS No.:
17680-84-1
Molecular Weight:
462.40
Formula:
C₂₂H₂₂O₁₁
SMILES:
COC1=C(C=C2C(=C1O)C(=O)C=C(O2)C3=CC=C(C=C3)O)OC4C(C(C(C(O4)CO)O)O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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