HSP990 (NVP-HSP990)

1 1

Selleck Chemicals

S7097-5MG

€144,00 EUR
€144,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

HSP990 (NVP-HSP990) is an inhibitor of HSP90 used in studies of Apoptosis. It is especially relevant in apoptosis, cancer, and cell cycle models, where defined compound exposure can be linked to caspase-associated cell-death signaling and survival decisions.

By inhibiting HSP90, HSP990 (NVP-HSP990) can be used to examine caspase-associated cell-death signaling and survival decisions. This context is compatible with apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HSP90
  • Pathway perturbation studies connected to Apoptosis
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in apoptosis, cancer, and cell cycle models

Overall, HSP990 (NVP-HSP990) is appropriate when a defined chemical perturbant is needed to connect HSP90 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HSP90
Target Class:
Other
Pathways:
Apoptosis
Research Area:
Apoptosis • Cancer • Cell Cycle • Protein Homeostasis
CAS No.:
934343-74-5
Molecular Weight:
379.39
Formula:
C₂₀H₁₈FN₅O₂
SMILES:
CC1=C2C(=NC(=N1)N)CC(NC2=O)C3=C(C=C(C=C3)F)C4=NC(=CC=C4)OC
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.