Hydroxyflutamide (Hydroxyniphtholide)

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Selleck Chemicals

SKU:S2174-5MG

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Hydroxyflutamide (Hydroxyniphtholide) is an antagonist of Adrenergic Receptors and Androgen Receptor used in studies of GPCR Signaling and Hormone Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics and ligand-dependent transcriptional programs and endocrine regulation in cancer, cardiovascular, and endocrinology models.

By blocking Adrenergic Receptors and Androgen Receptor, Hydroxyflutamide (Hydroxyniphtholide) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and ligand-dependent transcriptional programs and endocrine regulation. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cancer, cardiovascular, and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Adrenergic Receptors and Androgen Receptor
  • Pathway perturbation studies connected to GPCR Signaling and Hormone Signaling and related signaling programs
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Hydroxyflutamide (Hydroxyniphtholide) is appropriate when a defined chemical perturbant is needed to connect Adrenergic Receptors and Androgen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cardiovascular, and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Adrenergic Receptors • Androgen Receptor
Target Class:
GPCR
Pathways:
GPCR Signaling • Hormone Signaling • Neurotransmission
Research Area:
Cancer • Cardiovascular • Endocrinology • Neuroscience
CAS No.:
52806-53-8
Molecular Weight:
292.21
Formula:
C₁₁H₁₁F₃N₂O₄
SMILES:
CC(C)(O)C(=O)NC1=CC=C(C(=C1)C(F)(F)F)[N+]([O-])=O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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